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Hypotonic shocks activate rat TRPV4 in Yeast in the Absence of Polyunsaturated Fatty Acids

Transient-receptor-potential channels (TRPs) underlie the sensing of chemicals, heat, and mechanical force. We expressed the rat TRPV1 and TRPV4 subtypes in yeast and monitored their activities in vivo as Ca(2+) rise using transgenic aequorin. Heat and capsaicin activate TRPV1 but not TRPV4 in yeast...

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Hlavní autoři: Loukin, Stephen H., Su, Zhenwei, Kung, Ching
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825150/
https://ncbi.nlm.nih.gov/pubmed/19174160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.01.027
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