Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins

[Image: see text] Protein misfolding has been implicated in a large number of diseases termed protein- folding disorders (PFDs), which include Alzheimer’s disease, Parkinson’s disease, transmissible spongiform encephalopathies, familial amyloid polyneuropathy, Huntington’s disease, and type II diabe...

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Detalhes bibliográficos
Main Authors: Silva, Jerson L., Vieira, Tuane C. R. G., Gomes, Mariana P. B., Bom, Ana Paula Ano, Lima, Luis Mauricio T. R., Freitas, Monica S., Ishimaru, Daniella, Cordeiro, Yraima, Foguel, Debora
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825094/
https://ncbi.nlm.nih.gov/pubmed/19817406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar900179t
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