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Sec5 and Exo84 foster Oncogenic Ras-mediated Tumorigenesis
The genes encoding the Ras family of small GTPases are mutated to yield constitutively active GTP-bound oncogenic proteins in one-third of all human cancers. Oncogenic Ras binds to and activates a number of proteins that promote tumorigenic phenotypes, including the family of Ral guanine nucleotide...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824780/ https://ncbi.nlm.nih.gov/pubmed/20145037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0189 |
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