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The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis
Histone deacetylase inhibitors (HDACI) are promising anti-tumor agents. Although transcriptional deregulation is thought to be the main mechanism underlying their therapeutic effects, the exact mechanism and targets by which HDAC inhibitors achieve their anti-tumor effects remains poorly understood....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978070/ https://ncbi.nlm.nih.gov/pubmed/18794144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0188 |
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