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The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis

Histone deacetylase inhibitors (HDACI) are promising anti-tumor agents. Although transcriptional deregulation is thought to be the main mechanism underlying their therapeutic effects, the exact mechanism and targets by which HDAC inhibitors achieve their anti-tumor effects remains poorly understood....

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Bibliografski detalji
Glavni autori: Lee, Yi-Shan, Lim, Kian-Huat, Guo, Xing, Kawaguchi, Yoshiharu, Gao, Yasheng, Barrientos, Tomasa, Ordentlich, Peter, Wang, Xiao-Fan, Counter, Christopher, Yao, Tso-Pang
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978070/
https://ncbi.nlm.nih.gov/pubmed/18794144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0188
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