Targeting metabolic dependencies in pediatric cancer

著者: Issaq, Sameer H., Heske, Christine M.
出版年 Curr Opin Pediatr (2020)

Bioenergetic properties of human sarcoma cells help define sensitivity to metabolic inhibitors

著者: Issaq, Sameer H, Teicher, Beverly A, Monks, Anne
出版事項 2014

Sec5 and Exo84 foster Oncogenic Ras-mediated Tumorigenesis

著者: Issaq, Sameer H., Lim, Kian-Huat, Counter, Christopher M.
出版事項 2010

Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth

著者: Issaq, Sameer H., Mendoza, Arnulfo, Fox, Stephen D., Helman, Lee J.
出版年 Oncogenesis (2019)

Inhibition of nicotinamide phosphoribosyltransferase (NAMPT) with OT-82 induces DNA damage, cell death, and suppression of tumor growth in preclinical models of Ewing sarcoma

著者: Gibson, Anna E., Yeung, Choh, Issaq, Sameer H., Collins, Victor J., Gouzoulis, Michael, Zhang, Yiping, Ji, Jiuping, Mendoza, Arnulfo, Heske, Christine M.
出版年 Oncogenesis (2020)

EWS-FLI1-regulated serine synthesis and exogenous serine are necessary for Ewing sarcoma cellular proliferation and tumor growth

著者: Issaq, Sameer H., Mendoza, Arnulfo, Kidner, Ria, Rosales, Tracy, Duveau, Damien Y., Heske, Christine M., Rohde, Jason M., Boxer, Matthew B., Thomas, Craig J., DeBerardinis, Ralph J., Helman, Lee J.
出版年 Mol Cancer Ther (2020)

Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma

著者: Yeung, Choh, Gibson, Anna E., Issaq, Sameer H., Oshima, Nobu, Baumgart, Joshua T., Edessa, Leah D., Rai, Ganesha, Urban, Daniel J., Johnson, Michelle S., Benavides, Gloria A., Squadrito, Giuseppe L., Yohe, Marielle E., Lei, Haiyan, Eldridge, Sandy, Hamre, John, Dowdy, Tyrone, Ruiz-Rodado, Victor, Lita, Adrian, Mendoza, Arnulfo, Shern, Jack F., Larion, Mioara, Helman, Lee J., Stott, Gordon M., Krishna, Murali C., Hall, Matthew D., Darley-Usmar, Victor, Neckers, Leonard M., Heske, Christine M.
出版年 Cancer Res (2019)