Analysis of the role of PCNA-DNA contacts during clamp loading

BACKGROUND: Sliding clamps, such as Proliferating Cell Nuclear Antigen (PCNA) in eukaryotes, are ring-shaped protein complexes that encircle DNA and enable highly processive DNA replication by serving as docking sites for DNA polymerases. In an ATP-dependent reaction, clamp loader complexes, such as...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McNally, Randall, Bowman, Gregory D, Goedken, Eric R, O'Donnell, Mike, Kuriyan, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Research article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824762/
https://ncbi.nlm.nih.gov/pubmed/20113510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-3
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