Distinct Dose-Dependent Cortical Neuronal Migration and Neurite Extension Defects in Lis1 and Ndel1 Mutant Mice

Haploinsufficiency of LIS1 results in lissencephaly, a human neuronal migration disorder. LIS1 is a microtubule- (MT) and centrosome- [microtubule organizing center (MTOC)] associated protein that regulates nucleokinesis via the regulation of dynein motor function and localization. NDEL1 (NudE isofo...

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Bibliografiset tiedot
Päätekijät: Youn, Yong Ha, Pramparo, Tiziano, Hirotsune, Shinji, Wynshaw-Boris, Anthony
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2009
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824645/
https://ncbi.nlm.nih.gov/pubmed/20007476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4630-09.2009
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