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Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division

Mitotic spindle orientation and plane of cleavage in mammals is a determinant of whether division yields progenitor expansion and/or birth of new neurons during radial glial progenitor cell neurogenesis, but its role earlier in neuroepithelial stem cells is poorly understood. Here we report that Lis...

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Bibliografiske detaljer
Main Authors: Yingling, Jessica, Youn, Yong Ha, Darling, Dawn, Toyo-oka, Kazuhito, Pramparo, Tiziano, Hirotsune, Shinji, Wynshaw-Boris, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265303/
https://ncbi.nlm.nih.gov/pubmed/18267077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.026
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