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Lissencephaly: Mechanistic insights from animal models and potential therapeutic strategies
Lissencephaly is a severe human neuronal migration defect characterized by a smooth cerebral surface, mental retardation and seizures. The two most common genes mutated in patients with lissencephaly are LIS1 and DCX. LIS1 was the first gene cloned that was important for neuronal migration in any or...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967611/ https://ncbi.nlm.nih.gov/pubmed/20688183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.07.008 |
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