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Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer

Recent studies suggest that p53 binds predominantly to consensus sites composed of two decameric half-sites with zero spacing in vivo. Here we report the crystal structure of the p53 core domain bound to a full consensus site as a tetramer at 2.13Å resolution. Comparison with previously reported str...

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Detalhes bibliográficos
Main Authors: Chen, Yongheng, Dey, Raja, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824536/
https://ncbi.nlm.nih.gov/pubmed/20159469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.11.011
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