Relevant use of Klotho in FGF19 subfamily signaling system in vivo

α-Klotho (α-Kl) and its homolog, β-Klotho (β-Kl) are key regulators of mineral homeostasis and bile acid/cholesterol metabolism, respectively. FGF15/ humanFGF19, FGF21, and FGF23, members of the FGF19 subfamily, are believed to act as circulating metabolic regulators. Analyses of functional interact...

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Detalhes bibliográficos
Main Authors: Tomiyama, Ken-ichi, Maeda, Ryota, Urakawa, Itaru, Yamazaki, Yuji, Tanaka, Tomohiro, Ito, Shinji, Nabeshima, Yoko, Tomita, Tsutomu, Odori, Shinji, Hosoda, Kiminori, Nakao, Kazuwa, Imura, Akihiro, Nabeshima, Yo-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824417/
https://ncbi.nlm.nih.gov/pubmed/20080590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913986107
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