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Discovery of α-Klotho unveiled new insights into calcium and phosphate homeostasis

α-Klotho was first identified as the responsible gene in a mutant mouse line whose disruption results in a variety of premature aging-related phenotypes. α-Klotho has been shown to participate in the regulation of parathyroid hormone secretion and trans-epithelial transport of Ca(2+) in the choroid...

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Detalhes bibliográficos
Autor principal: Nabeshima, Yo-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The Japan Academy 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524302/
https://ncbi.nlm.nih.gov/pubmed/19282648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab/85.125
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