Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice

Etiology of endometrial cancer (EMC) is not fully understood. Animal models with rapidly and spontaneously developing EMC will help explore mechanisms of cancer initiation and progression. Pten(+/−) mice are currently being used as a model to study EMC. These females develop atypical endometrial hyp...

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Hlavní autoři: Daikoku, Takiko, Hirota, Yasushi, Tranguch, Susanne, Joshi, Ayesha R., DeMayo, Francesco J., Lydon, John P., Ellenson, Lora H., Dey, Sudhansu K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824329/
https://ncbi.nlm.nih.gov/pubmed/18632614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1274
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