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Conditional loss of uterine Pten unfailingly and rapidly induces endometrial cancer in mice

Etiology of endometrial cancer (EMC) is not fully understood. Animal models with rapidly and spontaneously developing EMC will help explore mechanisms of cancer initiation and progression. Pten(+/−) mice are currently being used as a model to study EMC. These females develop atypical endometrial hyp...

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Bibliografiske detaljer
Main Authors: Daikoku, Takiko, Hirota, Yasushi, Tranguch, Susanne, Joshi, Ayesha R., DeMayo, Francesco J., Lydon, John P., Ellenson, Lora H., Dey, Sudhansu K.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824329/
https://ncbi.nlm.nih.gov/pubmed/18632614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1274
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