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Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism
To construct a versatile model host for heterologous expression of genes encoding secondary metabolite biosynthesis, the genome of the industrial microorganism Streptomyces avermitilis was systematically deleted to remove nonessential genes. A region of more than 1.4 Mb was deleted stepwise from the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823899/ https://ncbi.nlm.nih.gov/pubmed/20133795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914833107 |
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