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A Computational Study of a Recreated G Protein-GEF Reaction Intermediate Competent for Nucleotide Exchange: Fate of the Mg Ion

Small G-proteins of the superfamily Ras function as molecular switches, interacting with different cellular partners according to their activation state. G-protein activation involves the dissociation of bound GDP and its replacement by GTP, in an exchange reaction that is accelerated and regulated...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ben Hamida-Rebaï, Mériam, Robert, Charles H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823772/
https://ncbi.nlm.nih.gov/pubmed/20174625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009142
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