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Nucleotide exchange factors: Kinetic analyses and the rationale for studying kinetics of GEFs

Exchange factors are enzymes that catalyze the exchange of GTP for GDP on guanine nucleotide binding proteins. Progress in understanding the molecular basis of action and the cellular functions of these enzymes has largely come from structural determinations (e.g., crystal structures) and studying e...

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Detalhes bibliográficos
Main Authors: Northup, John K., Jian, Xiaoying, Randazzo, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498072/
https://ncbi.nlm.nih.gov/pubmed/23181196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.21627
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