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Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes

The proteins that possess guanine nucleotide exchange factor (GEF) activity, which include about ~800 G protein coupled receptors (GPCRs),(1) 15 Arf GEFs,(2) 81 Rho GEFs,(3) 8 Ras GEFs,(4) and others for other families of GTPases,(5) catalyze the exchange of GTP for GDP on all regulatory guanine nuc...

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Detalhes bibliográficos
Main Authors: Randazzo, Paul A, Jian, Xiaoying, Chen, Pei-Wen, Zhai, Peng, Soubias, Olivier, Northup, John K
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187004/
https://ncbi.nlm.nih.gov/pubmed/25332840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.27609
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