Multiple Genetic Mechanisms Lead to Loss of Functional TbAT1 Expression in Drug-Resistant Trypanosomes

The P2 aminopurine transporter, encoded by TbAT1 in African trypanosomes in the Trypanosoma brucei group, carries melaminophenyl arsenical and diamidine drugs into these parasites. Loss of this transporter contributes to drug resistance. We identified the genomic location of TbAT1 to be in the subte...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Stewart, Mhairi L., Burchmore, Richard J. S., Clucas, Caroline, Hertz-Fowler, Christiane, Brooks, Karen, Tait, A., MacLeod, A., Turner, C. Michael R., De Koning, Harry P., Wong, Pui Ee, Barrett, Michael P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2010
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823006/
https://ncbi.nlm.nih.gov/pubmed/19966032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00200-09
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller