Genotypic Status of the TbAT1/P2 Adenosine Transporter of Trypanosoma brucei gambiense Isolates from Northwestern Uganda following Melarsoprol Withdrawal

BACKGROUND: The development of arsenical and diamidine resistance in Trypanosoma brucei is associated with loss of drug uptake by the P2 purine transporter as a result of alterations in the corresponding T. brucei adenosine transporter 1 gene (TbAT1). Previously, specific TbAT1 mutant type alleles l...

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Detalhes bibliográficos
Main Authors: Kazibwe, Anne J. N., Nerima, Barbara, de Koning, Harry P., Mäser, Pascal, Barrett, Michael P., Matovu, Enock
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745678/
https://ncbi.nlm.nih.gov/pubmed/19787038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000523
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