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Conjugate Addition/Ireland–Claisen Rearrangements of Allyl Fumarates: Simple Access to Terminally Differentiated Succinates

[Image: see text] The conjugate addition of dialkylzinc reagents to allyl fumarates with subsequent Ireland–Claisen rearrangement has been accomplished yielding substituted unsymmetrical succinic acid derivatives. This one-pot reaction creates two new carbon–carbon bonds at contiguous stereogenic ce...

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Detalhes bibliográficos
Main Authors: Bausch, Cory C., Johnson, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822989/
https://ncbi.nlm.nih.gov/pubmed/18211081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo701778k
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