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Ciliate telomerase RNA loop IV nucleotides promote hierarchical RNP assembly and holoenzyme stability

Telomerase adds simple-sequence repeats to chromosome 3′ ends to compensate for the loss of repeats with each round of genome replication. To accomplish this de novo DNA synthesis, telomerase uses a template within its integral RNA component. In addition to providing the template, the telomerase RNA...

詳細記述

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書誌詳細
主要な著者: Robart, Aaron R., O'Connor, Catherine M., Collins, Kathleen
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822921/
https://ncbi.nlm.nih.gov/pubmed/20106956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1936410
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