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Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65

Telomerase is a ribonucleoprotein complex essential for maintenance of telomere DNA at linear chromosome ends. The catalytic core of Tetrahymena telomerase comprises a ternary complex of telomerase RNA (TER), telomerase reverse transcriptase (TERT), and the essential La family protein p65. NMR and c...

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Bibliografiske detaljer
Main Authors: Singh, Mahavir, Wang, Zhonghua, Koo, Bon-Kyung, Patel, Anooj, Cascio, Duilio, Collins, Kathleen, Feigon, Juli
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398246/
https://ncbi.nlm.nih.gov/pubmed/22705372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.018
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