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Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1

Shq1 is an essential protein involved in the early steps of biogenesis and assembly of H/ACA RNPs. Shq1 binds to dyskerin (Cbf5 in yeast) at an early step of H/ACA RNP assembly and is subsequently displaced by the H/ACA RNA. Shq1 contains an N-terminal CS and a C-terminal Shq1-specific domain (SSD)....

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Singh, Mahavir, Wang, Zhonghua, Cascio, Duilio, Feigon, Juli
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323627/
https://ncbi.nlm.nih.gov/pubmed/25553844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.12.012
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