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Ciliate telomerase RNA loop IV nucleotides promote hierarchical RNP assembly and holoenzyme stability
Telomerase adds simple-sequence repeats to chromosome 3′ ends to compensate for the loss of repeats with each round of genome replication. To accomplish this de novo DNA synthesis, telomerase uses a template within its integral RNA component. In addition to providing the template, the telomerase RNA...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822921/ https://ncbi.nlm.nih.gov/pubmed/20106956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1936410 |
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