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Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa

BACKGROUND: The efficacy of BCG may be enhanced by heterologous vaccination strategies that boost the BCG-primed immune response. One leading booster vaccine, MVA85A, has shown promising safety and immunogenicity in UK human trials. We investigated the safety and immunogenicity of MVA85A in mycobact...

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Détails bibliographiques
Auteurs principaux: Hawkridge, Tony, Scriba, Thomas J., Gelderbloem, Sebastian, Smit, Erica, Tameris, Michele, Moyo, Sizulu, Lang, Trudie, Veldsman, Ashley, Hatherill, Mark, van der Merwe, Linda, Fletcher, Helen A, Mahomed, Hassan, Hill, Adrian V.S., Hanekom, Willem A., Hussey, Gregory D., McShane, Helen
Format: Artigo
Langue:Inglês
Publié: 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822902/
https://ncbi.nlm.nih.gov/pubmed/18582195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/590185
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