MVA85A, a novel TB vaccine, is safe in adolescents and children, and induces complex subsets of polyfunctional CD4+ T cells

MVA85A is a new tuberculosis vaccine aimed at enhancing immunity induced by BCG. We investigated the safety and immunogenicity of MVA85A in healthy adolescents and children from a tuberculosis endemic region, who received BCG at birth. Twelve adolescents and 24 children were vaccinated and followed...

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Bibliografiset tiedot
Päätekijät: Scriba, Thomas J., Tameris, Michele, Mansoor, Nazma, Smit, Erica, van der Merwe, Linda, Isaacs, Fatima, Keyser, Alana, Moyo, Sizulu, Brittain, Nathaniel, Lawrie, Alison, Gelderbloem, Sebastian, Veldsman, Ashley, Hatherill, Mark, Hawkridge, Anthony, Hill, Adrian V.S., Hussey, Gregory D., Mahomed, Hassan, McShane, Helen, Hanekom, Willem A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044835/
https://ncbi.nlm.nih.gov/pubmed/20017188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939754
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