Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa

BACKGROUND: The efficacy of BCG may be enhanced by heterologous vaccination strategies that boost the BCG-primed immune response. One leading booster vaccine, MVA85A, has shown promising safety and immunogenicity in UK human trials. We investigated the safety and immunogenicity of MVA85A in mycobact...

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Autori principali: Hawkridge, Tony, Scriba, Thomas J., Gelderbloem, Sebastian, Smit, Erica, Tameris, Michele, Moyo, Sizulu, Lang, Trudie, Veldsman, Ashley, Hatherill, Mark, van der Merwe, Linda, Fletcher, Helen A, Mahomed, Hassan, Hill, Adrian V.S., Hanekom, Willem A., Hussey, Gregory D., McShane, Helen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822902/
https://ncbi.nlm.nih.gov/pubmed/18582195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/590185
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