Smoking and colorectal cancer in Lynch syndrome: Results from the Colon Cancer Family Registry and The University of Texas M. D. Anderson Cancer Center

PURPOSE: Lynch syndrome family members with inherited germline mutations in DNA mismatch repair (MMR) genes have a high risk of colorectal cancer (CRC) and cases typically have tumors that exhibit a high level of microsatellite instability (MSI). There is some evidence that smoking is a risk factor...

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Autors principals: Pande, Mala, Lynch, Patrick M., Hopper, John L., Jenkins, Mark A., Gallinger, Steve, Haile, Robert W., LeMarchand, Loic, Lindor, Noralane M., Campbell, Peter T., Newcomb, Polly A., Potter, John D., Baron, John A., Frazier, Marsha L., Amos, Christopher I.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822883/
https://ncbi.nlm.nih.gov/pubmed/20145170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1877
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