Do the risks of Lynch syndrome-related cancers depend on the parent of origin of the mutation?

BACKGROUND: Individuals who carry pathogenic mutations in DNA mismatch repair (MMR) genes have high risks of cancer, and small studies have suggested that these risks depend on the sex of the parent from whom the mutation was inherited. We have conducted the first large study of such a parent-of-ori...

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Gepubliceerd in:Fam Cancer
Hoofdauteurs: Gemechu, Shimelis Dejene, van Vliet, Christine M., Win, Aung Ko, Figueiredo, Jane C., Marchand, Loic Le, Gallinger, Steven, Newcomb, Polly A., Hopper, John L., Lindor, Noralane M., Jenkins, Mark A., Dowty, James G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410789/
https://ncbi.nlm.nih.gov/pubmed/32107660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-020-00167-4
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