Childhood cancers in families with and without Lynch syndrome

BACKGROUND: Inheritance of a germline mutation in one of the DNA mismatch repair (MMR) genes or the EPCAM gene is associated with an increased risk of colorectal cancer, endometrial cancer, and other adult malignancies (Lynch syndrome). The risk of childhood cancers in Lynch syndrome families, howev...

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Publié dans:Fam Cancer
Auteurs principaux: Heath, John A., Reece, Jeanette C., Buchanan, Daniel D., Casey, Graham, Durno, Carol A., Gallinger, Steven, Haile, Robert W., Newcomb, Polly A., Potter, John D., Thibodeau, Stephen N., Le Marchand, Loïc, Lindor, Noralane M., Hopper, John L., Jenkins, Mark A., Win, Aung Ko
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631656/
https://ncbi.nlm.nih.gov/pubmed/25963852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9810-3
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