Childhood cancers in families with and without Lynch syndrome

BACKGROUND: Inheritance of a germline mutation in one of the DNA mismatch repair (MMR) genes or the EPCAM gene is associated with an increased risk of colorectal cancer, endometrial cancer, and other adult malignancies (Lynch syndrome). The risk of childhood cancers in Lynch syndrome families, howev...

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Gepubliceerd in:Fam Cancer
Hoofdauteurs: Heath, John A., Reece, Jeanette C., Buchanan, Daniel D., Casey, Graham, Durno, Carol A., Gallinger, Steven, Haile, Robert W., Newcomb, Polly A., Potter, John D., Thibodeau, Stephen N., Le Marchand, Loïc, Lindor, Noralane M., Hopper, John L., Jenkins, Mark A., Win, Aung Ko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631656/
https://ncbi.nlm.nih.gov/pubmed/25963852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9810-3
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