Childhood cancers in families with and without Lynch syndrome

BACKGROUND: Inheritance of a germline mutation in one of the DNA mismatch repair (MMR) genes or the EPCAM gene is associated with an increased risk of colorectal cancer, endometrial cancer, and other adult malignancies (Lynch syndrome). The risk of childhood cancers in Lynch syndrome families, howev...

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Detalhes bibliográficos
Publicado no:Fam Cancer
Main Authors: Heath, John A., Reece, Jeanette C., Buchanan, Daniel D., Casey, Graham, Durno, Carol A., Gallinger, Steven, Haile, Robert W., Newcomb, Polly A., Potter, John D., Thibodeau, Stephen N., Le Marchand, Loïc, Lindor, Noralane M., Hopper, John L., Jenkins, Mark A., Win, Aung Ko
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631656/
https://ncbi.nlm.nih.gov/pubmed/25963852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-015-9810-3
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