Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1

Accumulating data suggest that matrix metalloproteinases (MMPs) may be important mediators in the pathophysiology of acute brain injury after trauma or stroke. Here, we test the hypothesis that the endogenous tissue inhibitor of metalloproteinase (TIMP-1) is neuroprotective in vitro and in vivo. For...

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Autors principals: Tejima, Emiri, Guo, Shuzhen, Murata, Yoshihiro, Arai, Ken, Lok, Josephine, van Leyen, Klaus, Rosell, Anna, Wang, Xiaoying, Lo, Eng H.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822804/
https://ncbi.nlm.nih.gov/pubmed/19469687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.0959
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