Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1

Accumulating data suggest that matrix metalloproteinases (MMPs) may be important mediators in the pathophysiology of acute brain injury after trauma or stroke. Here, we test the hypothesis that the endogenous tissue inhibitor of metalloproteinase (TIMP-1) is neuroprotective in vitro and in vivo. For...

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Detalhes bibliográficos
Main Authors: Tejima, Emiri, Guo, Shuzhen, Murata, Yoshihiro, Arai, Ken, Lok, Josephine, van Leyen, Klaus, Rosell, Anna, Wang, Xiaoying, Lo, Eng H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822804/
https://ncbi.nlm.nih.gov/pubmed/19469687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.0959
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