Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1

Accumulating data suggest that matrix metalloproteinases (MMPs) may be important mediators in the pathophysiology of acute brain injury after trauma or stroke. Here, we test the hypothesis that the endogenous tissue inhibitor of metalloproteinase (TIMP-1) is neuroprotective in vitro and in vivo. For...

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Bibliographic Details
Main Authors: Tejima, Emiri, Guo, Shuzhen, Murata, Yoshihiro, Arai, Ken, Lok, Josephine, van Leyen, Klaus, Rosell, Anna, Wang, Xiaoying, Lo, Eng H.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822804/
https://ncbi.nlm.nih.gov/pubmed/19469687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.0959
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