Chargement en cours...
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
The classical nonhomologous end-joining (C-NHEJ) DNA double-strand break (DSB) repair pathway employs the Ku70/80 complex (Ku) for DSB recognition and the XRCC4/DNA ligase 4 (Lig4) complex for ligation. During IgH class switch recombination (CSR) in B lymphocytes, switch (S) region DSBs are joined b...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2010
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822597/ https://ncbi.nlm.nih.gov/pubmed/20142431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092449 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|