Llwytho...

Targeted disruption of NF-κB1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling

NF-κB-mediated proinflammatory response to cigarette smoke (CS) plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). The heterodimer of RelA/p65-p50 (subunits of NF-κB) is involved in transactivation of NF-κB-dependent genes, but interestingly p50 has no transact...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rajendrasozhan, Saravanan, Chung, Sangwoon, Sundar, Isaac K., Yao, Hongwei, Rahman, Irfan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822556/
https://ncbi.nlm.nih.gov/pubmed/19965984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00265.2009
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