DNA topoisomerase-targeting antitumor drugs can be studied in yeast.
The antitumor drugs camptothecin and an anilinoacridine, 4'-(9-acridinylamino)-methanesulfon-m-anisidide (mAMSA), which act on DNA topoisomerase I and II, respectively, are shown to inhibit the growth of Saccharomyces cerevisiae mutants selected for their permeability to other inhibitors. In additio...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282219/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7501 |
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