Genetic analysis of mutations that compensate for loss of Escherichia coli DNA topoisomerase I.

A transposon Tn10 insertion in topA, the structural gene of Escherichia coli DNA topoisomerase I, behaves as an excluded marker in genetic crosses with many strains of E. coli. However, derivative strains that accept this mutant topA allele are readily selected. We show that many of these topA mutan...

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Bibliografiske detaljer
Main Authors: Raji, A, Zabel, D J, Laufer, C S, Depew, R E
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC215900/
https://ncbi.nlm.nih.gov/pubmed/2987184
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