Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function

BACKGROUND & AIMS: Di-α hydroxy bile salt, sodium chenodeoxycholate (CDC), and bile acid (BA) binding have unclear effects on colonic transit in health and disease. METHODS: We performed 2 randomized, double-blind, placebo-controlled studies. In healthy volunteers (20/group), we evaluated effect...

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Autori principali: Odunsi-Shiyanbade, Suwebatu T., Camilleri, Michael, McKinzie, Sanna, Burton, Duane, Carlson, Paula, Busciglio, Irene A., Lamsam, Jesse, Singh, Ravinder, Zinsmeister, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822105/
https://ncbi.nlm.nih.gov/pubmed/19879973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2009.10.020
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