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Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during β-adrenergic stimulation
β-Adrenergic receptor (β-AR) stimulation of cardiac muscle has been proposed to enhance Ca(2+) release from the sarcoplasmic reticulum (SR) through ryanodine receptors (RyRs). However, the anticipated increase in RyR Ca(2+) sensitivity has proven difficult to study in intact cardiomyocytes, due to a...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821561/ https://ncbi.nlm.nih.gov/pubmed/19900959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.181800 |
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