K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes

K201 has previously been shown to reduce diastolic contractions in vivo during β-adrenergic stimulation and elevated extracellular calcium concentration ([Ca(2+)](o)). The present study characterised the effect of K201 on electrically stimulated and spontaneous diastolic sarcoplasmic reticulum (SR)-...

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Bibliographic Details
Main Authors: Elliott, E. B., Hasumi, H., Otani, N., Matsuda, T., Matsuda, R., Kaneko, N., Smith, G. L., Loughrey, Christopher M.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2011
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Original Contribution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228956/
https://ncbi.nlm.nih.gov/pubmed/21901290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0218-4
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