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Increased Ca(2+) leak and spatiotemporal coherence of Ca(2+) release in cardiomyocytes during β-adrenergic stimulation

β-Adrenergic receptor (β-AR) stimulation of cardiac muscle has been proposed to enhance Ca(2+) release from the sarcoplasmic reticulum (SR) through ryanodine receptors (RyRs). However, the anticipated increase in RyR Ca(2+) sensitivity has proven difficult to study in intact cardiomyocytes, due to a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ogrodnik, Jakob, Niggli, Ernst
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821561/
https://ncbi.nlm.nih.gov/pubmed/19900959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.181800
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