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Design of high-affinity S100-target hybrid proteins
S100B and S100A10 are dimeric, EF-hand proteins. S100B undergoes a calcium-dependant conformational change allowing it to interact with a short contiguous sequence from the actin-capping protein CapZ (TRTK12). S100A10 does not bind calcium but is able to recruit the N-terminus of annexin A2 importan...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821271/ https://ncbi.nlm.nih.gov/pubmed/19827097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.267 |
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