The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases

Interferon (IFN) signaling is initiated by the recognition of viral components by host pattern recognition receptors. Dengue virus (DEN) triggers IFN-β induction through a molecular mechanism involving the cellular RIG-I/MAVS signaling pathway. Here we report that the MAVS protein level is reduced i...

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Bibliographische Detailangaben
Hauptverfasser: Yu, Chia-Yi, Chiang, Ruei-Lin, Chang, Tsung-Hsien, Liao, Ching-Len, Lin, Yi-Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820939/
https://ncbi.nlm.nih.gov/pubmed/20032188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02174-09
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