Enterovirus 71 Proteins 2A and 3D Antagonize the Antiviral Activity of Gamma Interferon via Signaling Attenuation

Enterovirus 71 (EV71) infection causes severe mortality involving multiple possible mechanisms, including cytokine storm, brain stem encephalitis, and fulminant pulmonary edema. Gamma interferon (IFN-γ) may confer anti-EV71 activity; however, the claim that disease severity is highly correlated to a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wang, Li-Chiu, Chen, Su-O, Chang, Shih-Ping, Lee, Yi-Ping, Yu, Chun-Keung, Chen, Chia-Ling, Tseng, Po-Chun, Hsieh, Chia-Yuan, Chen, Shun-Hua, Lin, Chiou-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473548/
https://ncbi.nlm.nih.gov/pubmed/25926657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00205-15
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