Enterovirus 71 Proteins 2A and 3D Antagonize the Antiviral Activity of Gamma Interferon via Signaling Attenuation

Enterovirus 71 (EV71) infection causes severe mortality involving multiple possible mechanisms, including cytokine storm, brain stem encephalitis, and fulminant pulmonary edema. Gamma interferon (IFN-γ) may confer anti-EV71 activity; however, the claim that disease severity is highly correlated to a...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Wang, Li-Chiu, Chen, Su-O, Chang, Shih-Ping, Lee, Yi-Ping, Yu, Chun-Keung, Chen, Chia-Ling, Tseng, Po-Chun, Hsieh, Chia-Yuan, Chen, Shun-Hua, Lin, Chiou-Feng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473548/
https://ncbi.nlm.nih.gov/pubmed/25926657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00205-15
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