The Interferon Stimulator Mitochondrial Antiviral Signaling Protein Facilitates Cell Death by Disrupting the Mitochondrial Membrane Potential and by Activating Caspases

Interferon (IFN) signaling is initiated by the recognition of viral components by host pattern recognition receptors. Dengue virus (DEN) triggers IFN-β induction through a molecular mechanism involving the cellular RIG-I/MAVS signaling pathway. Here we report that the MAVS protein level is reduced i...

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Detalhes bibliográficos
Main Authors: Yu, Chia-Yi, Chiang, Ruei-Lin, Chang, Tsung-Hsien, Liao, Ching-Len, Lin, Yi-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820939/
https://ncbi.nlm.nih.gov/pubmed/20032188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02174-09
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