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Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation of interferon regulatory factor 3 (IRF3) triggered by viral infection and by foreign DNA and RNA stimulation was blocked by DEN-encoded NS2B3 through a proteas...

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書誌詳細
主要な著者: Yu, Chia-Yi, Chang, Tsung-Hsien, Liang, Jian-Jong, Chiang, Ruei-Lin, Lee, Yi-Ling, Liao, Ching-Len, Lin, Yi-Ling
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386177/
https://ncbi.nlm.nih.gov/pubmed/22761576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002780
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