Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation of interferon regulatory factor 3 (IRF3) triggered by viral infection and by foreign DNA and RNA stimulation was blocked by DEN-encoded NS2B3 through a proteas...

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Detalhes bibliográficos
Principais autores: Yu, Chia-Yi, Chang, Tsung-Hsien, Liang, Jian-Jong, Chiang, Ruei-Lin, Lee, Yi-Ling, Liao, Ching-Len, Lin, Yi-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386177/
https://ncbi.nlm.nih.gov/pubmed/22761576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002780
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