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Infection of Cell Lines with Experimental and Natural Ovine Scrapie Agents
Mouse bioassay remains the gold standard for determining proof of infectivity, strain type, and infectious titer estimation in prion disease research. The development of an approach using ex vivo cell-based assays remains an attractive alternative, both in order to reduce the use of mice and to hast...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820909/ https://ncbi.nlm.nih.gov/pubmed/20032176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01855-09 |
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