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Aquaporin-1 Tunes Pain Perception by Interaction with Na(v)1.8 Na(+) Channels in Dorsal Root Ganglion Neurons
Aquaporin-1 (AQP1) water channels are expressed in the plasma membrane of dorsal root ganglion (DRG) neurons. We found reduced osmotic water permeability in freshly isolated DRG neurons from AQP1(−/−) versus AQP1(+/+) mice. Behavioral studies showed greatly reduced thermal inflammatory pain percepti...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820815/ https://ncbi.nlm.nih.gov/pubmed/20018876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.090233 |
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